Looks ok to me, as long as you get the IP addresses correct and understand the route of the IP's through your network.As previous comment mentioned, careful thought needs to considered on what interface to place these.

Any other devices attached to same interface on the switch?  Try entering "show port-security address" and see if the MAC matches up with the MAC on the device.

Portfast shouldnt used on a switch to switch link.As it effectively brings up a port as soon as an end device is detected it allows loops to form if used on a switch to switch link and makes STP redundant. So to answer your question, yes disable port...

BPDUGuard is likely enabled on at least one of these ports. Try manually disabling on both and test again."Show spanning-tree int XXXX detail" should show if this is enabled or not.

Agree with Leo, we see this quite frequently when we have non-CDP devices inbetween the source of the CDP and other CDP devices.