I work daily with two computers, one in the corporate network and one personal sitting on open internet. Keyboard / mouse switch to control them both.
I use audio on the personal PC only as the corp VPN not great for audio quality.
So I call a colleague on webex teams, all good, then I share the screen on the corp PC and the audio is automatically enabled, we get bad feedback.
So muting and silencing corp PC audio fixes that, problem is then I miss meetings as I cannot hear the reminders.