There are no options to alter DNACs behaviour in the infoblox integration. Any solution to this will have to be on the infoblox side.
I am not an infoblox expert, but the last time I looked at this i concluded that "writes" to infoblox is slow and there is not too much one can do about it(assuming that your infoblox instance has the resources it requires). 5 minutes still seems excessive to me - is there a proxy between your DNAC and Infoblox that could be enforcing a rate-limit?
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