From the CLI of the ESA itself - no, this is not possible, as we do not honor the pipe command option.
You can see all the CLI references for the versions here:
http://www.cisco.com/c/en/us/support/security/email-security-appliance/products-command-reference-list.html
Externally - you can script this to call and reference commands via SSH, example:
$ ssh admin@192.168.0.189 workqueue status
Status as of: Fri Sep 11 18:01:36 2015 EDT
Status: Operational
Messages: 0
You can get more enhanced/complex w/ the commands you run - just need to trial and error what you are specifically after and assure your results.
Example would be, as you wanted - to mail from the CLI:
$ ssh admin@192.168.0.189 workqueue status | mail -s "Workqueue Status" robert@example.com
With my mail received being:
In order to best operate this, you can setup SSH public key, in order to save hash in order to make quick log-in, not use password for scripting from internal hosts:
http://www.cisco.com/c/en/us/support/docs/security/email-security-appliance/118305-technote-esa-00.html
-Robert