Hi Gandhi,
It sounds like there may be a DNS resolution issue on your network. To confirm whether your device can find the MX records for the domain, follow the steps below.
Welcome to the Cisco IronPort X1070 Messaging Gateway(tm) Appliance
ironport> nslookup
Please enter the host or IP address to resolve.
[]> yahoo.co.jp
Choose the query type:
1. A the host's IP address
2. AAAA the host's IPv6 address
3. CNAME the canonical name for an alias
4. MX the mail exchanger
5. NS the name server for the named zone
6. PTR the hostname if the query is an Internet address,
otherwise the pointer to other information
7. SOA the domain's "start-of-authority" information
8. TXT the text information
[1]> 4
MX=mx1.mail.yahoo.co.jp PREF=10 TTL=30m
MX=mx2.mail.yahoo.co.jp PREF=10 TTL=30m
MX=mx3.mail.yahoo.co.jp PREF=10 TTL=30m
MX=mx5.mail.yahoo.co.jp PREF=10 TTL=30m
ironport>