There should not be an issue to update the VMWare tools. You should be able to install them. Underlying OS in CPI is ADE-OS/Linux.
Check this thread which has the same question :
https://supportforums.cisco.com/discussion/11676511/vmware-tools-cisco-prime-infrastructure
-Thanks
Vinod
** Encourage Contributors. RATE them. **
-Thanks
Vinod
**Rating Encourages contributors, and its really free. **