Hi
I bit confuse with you problem. What did you say is that a machine plugged on the switch port, lost SSH connectivity to this switch after you enabled dot1x on that port?
You mentioned NAD and ISE which means they are not the same on your environment? Cause ISE is a NAD.
When you enable dot1x you can push dynamic acl to the interface and this could cause blocking. But I dont believe really that is the problem.