Hello,
Only the switch that is directly connected
to the NPV enabled switches needs to be enabled for NPIV.
NPIV provides a means to assign multiple FC IDs to a single N port which in this case would only be done on a single core MDS 9513 Director. NPV on the other hand, aggregates multiple locally connected N ports into one or more external NP links, which shares the domain ID of the NPIV enabled switch.
Refer to the following for more info:
http://www.cisco.com/en/US/docs/switches/datacenter/mds9000/sw/4_1/configuration/guides/cli_4_1/npv.html
Hope this helps!
Nikhil