Overrun indicates that the input rate exceeded the receiver's ability to handle the data. You can try the following:
1. Increase input queue size.
2. Move the server to a line card which has bigger RX buffer.
3. If QoS is enabled on port, check which queue has drop. If possible, allocate more resource to that queue.
4. Investigate the traffic to see if all of them is necessary.
5. Turn on flow control if it is supported on both sides.