Hi Junior,
The answer is: "It depends upon the hardware you are connecting to, and your network infrastructure"
From a locally switched perspective you need to look at the backplane speed of the switches that are directly attached to your VMHosts, and whether there is any oversubscription of ports (as there are on several switches / line cards). Then you need to know the path that the traffic will take, and therefore the speed of the uplinks, and the speed of your distribution & backbone.
I'm afraid the question is far too ambiguous to provide a meaningful answer.
Nick