Do you mean use reflexive acl for traffic going out to the internet from internal clients to allow return traffic back in and at the same time allow connections from outside to a specific inside server for certain ports ?
If so yes you should be able to do that.
Basically your acl applied inbound on your outside interface would allow the traffic to your web server and nothing else and the reflexive acl part then adds temporary entries to that acl for return traffic to clients.
Is this what you are asking ?
Jon
