Hi,
yes you can using PBR.
access-list 100 permit tcp any any eq 80
access-list 100 permit tcp any any eq 8080
access-list 100 permit tcp any any eq 443
access-list 110 permit tcp any any eq smtp
route-map PBR permit 10
match ip address 100
set ip next-hop x.x.x.x where x.x.x.x is ISP1 next-hop
route-map PBR permit 20
match ip address 110
set ip next-hop y.y.y.y where y.y.y.y is ISP2 next-hop
int fx/x
ip policy route-map PBR where fx/x is your router LAN ip address
if you are doing NAT then you'll have to do this also
route-map ISP1
match interface
route-map ISP2
match interface
ip nat inside source route-map ISP1 interface
ip nat inside source route-map ISP2 interface
Regards.
Alain.
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