Your computer may slow or stop responding and repeatedly log event IDs 9582 and 1160 in Exchange 2000 Server
http://support.microsoft.com/default.aspx?scid=kb;en-us;838233
"To resolve this problem, obtain the August 2004 Exchange 2000 Server Post-Service Pack 3 update rollup."
How to troubleshoot virtual memory fragmentation in Exchange Server 2003 and Exchange 2000 Server
http://support.microsoft.com/default.aspx?scid=kb;en-us;325044
Virtual memory fragmentation events are logged every hour on a computer that is running Exchange Server 2000 (March 15, 2005)
http://support.microsoft.com/default.aspx?scid=kb;en-us;883527
"A supported hotfix is now available from Microsoft, but it is only intended to correct the problem that is described in this article."