Cisco IP phones use the Selsius Skinny Station Protocol to connect with and register to the Cisco CallManager (CCM). Messages flow back and forth that include IP address and port information used to identify other IP phone users with which a call can be placed.
To be able to deploy Cisco IOS NAT between the IP phone and CCM in a scalable environment, NAT needs to be able to detect the Selsius Skinny Station Protocol and understand the information passed within the messages.
When an IP phone attempts to connect to the CCM and it matches the configured NAT translation rules, NAT will translate the original source IP address and replace it with one from the configured pool. This new address will be reflected in the CCM and be visible to other IP phone users
http://www.cisco.com/en/US/products/sw/iosswrel/ps1834/products_feature_guide09186a008008052e.html
