Hi,
Generally, the advice concerning anti-virus software is:
1. Completely disable during LMS installation
2. Exclude everything under CSCOpx from real-time scans
It is possible that additional settings will impact LMS so I suggest a look and see approach. Try enabling the feature and watch the event logs for problems. If the software has a 'warn' only option enable that first. It should give you a good idea of what it is doing.
Thanks,
Nick