We used the SG 200-26P (firmware 1.1.1.8 ) as our main LAN switch. We have a few other 100Mb switches but our servers and nodes in our cluster are all on this switch. If you log onto a machine on one of the other 100Mb switches and then Remote Desktop to a virtual machine that is running off the SG 200-26P, and then copy say a large file (500Mb) your you will get major delays in the response time. For instance mouse clicks, screen paints, etc. Remote Desktop to a VM is unusable during this time period. This also happens for instance during backups when files are being copied from a machine to a VM.
As mentioned the other switches are 100Mb switches from HP, a bit old. I didn't change much in the setup of the SG 200-26P our of the box. Jumbo frames is disabled, RSTP is enabled, with Flooding for BPDU handling.
I haven't seen this before in a switch and this problems has been noticed recently. Not sure when it started happening.