Hi Tia,
netflow tuning is similar to QoS tuning meaning that there is no setting which is good for every implementation but it depends on traffic pattern and on the hardware being utilized.
In general you use fast aging when TCAM is getting full and you need to clear space to fit more flows and get more accurate information (if the TCAM is full new flows are not created).
The drawback is that the shorter the flows stay in the TCAM and 'statistically' the higher the CPU will go as in a unit of time it needs to create and delete an higher number of flows (and depending on hw and configuration it might export them to a collector).
If you don't see high CPU condition when you configure a more aggressive aging it means that 1) your hardware can cope with the traffic pattern and 2) there aren't some many new unique flos created in a unit of time.
Riccardo