One of the server hosted at Site-A , not able to connect the application which is hosted at Site-B Server , there is no firewall in between.Server IP's are pingable from both the end. See the below trace route from SITE-A to SITE-B and vice versa. based on below trace result we can see that there is some asymmetric route beween these two sites.
Does asymmetric routing can affect application operation?
Asymmetric routing occurs when transmit and receive packets follow different paths between a host and the peer with which it communicates. In your scenario, if you see a different path when you traceroute to server B from server A and vice versa, it indicates asymmetric routing .
Asymmetric routing can lead to issues like unicast flooding ,missing MLS entries, latency and drops. The below link provides a detailed explanation about asymmetric routing:
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