I had the same issue, after setting up a recycled lab ASA... First, check the time of the ASA, and configure NTP or set at least the time manually (probably one day in the past, just to make sure you don't get any issues with time zone, and the certi...

This initial bug was fixed a long time ago. If you face the same error message again in 2025 (...), after updating to ISE 3.1 Patch 10, you might need to rollback the patch... This is a known bug: https://bst.cloudapps.cisco.com/bugsearch/bug/CSCwn93...

I got a similar warning during the Update from 2.6 p10 to 3.1. But the problem solved automatically. I did a full ipgrade of a pair of ISE. After the primary was updated, I remained logged in at the secondary (while monitoring the status under Admini...