Hey @PutmanoAIT,
I think it is possible to integrate both Palo Alto Firewall and F5 Load Balancer into a Cisco ACI infrastructure. Traffic from the client via L3Out will be routed through the Palo Alto Firewall and then to the F5 VIP. This is a common deployment scenario and can be achieved using a service graph in Cisco ACI.
You can create a service graph that includes both the Palo Alto Firewall and the F5 Load Balancer. The traffic will first be directed to the Palo Alto Firewall for filtering, and then to the F5 Load Balancer for load balancing.
Cheers!