We have a couple options depending on whether you are doing
1) Lab Evaluation or Production Deployment
2) VMware vCenter 6.x or other Hypervisors
It should be clear from the naming in the Software Download area which is for which.
Please see the ISE Installation Guide for supported hypervisors and minimum requirements. It also talks about Network Deployments in Cisco ISE so you can understand the personas and sizing including Standalone and Distributed ISE Deployments
Also see Getting Started with ISE for initial setup. There is also a great YouTube video Installing ISE 2.4 on VMWare vCenter 6.5 from OVA Package using the OVF Tool if that works for you.
