Hi,
You can manually create on both sides but we always recommend configuring by using the NDO in multi-site.
If you configure on both sides, this is simply a Layer2 extension via EPG Static Path. Need to be cautious that without MSO/NDO you don't have any ability to limit flooding behavior between these fabrics. NDO can help protect your fabric against flooding and benefit on making changes on both sites.
Best Regards
Lucy
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