Hi @axfalk
Below is a copy-paste from APIC GUI, which is pretty descriptive
Fabric policies
Fabric policies govern the operation of internal fabric interfaces. The system provides default fabric policies. Fabric policies enable configuring various functions or protocols. Administrators who have fabric administrator privileges can create new fabric policies according to their requirements. The APIC enables administrators to select the pods, leaf switches, and interfaces to which they will apply access policies.
Fabric policies configure interfaces that connect spine and leaf switches. Fabric policies can enable features such as monitoring (statistics collection and statistics export), troubleshooting (on-demand diagnostics and SPAN), or NTP.
Access policies
Access policies govern the operation of interfaces that provide external access to the fabric. The system provides default access policies. Access policies enable configuring various functions or protocols. Administrators who have fabric administrator privileges can create new access policies according to their requirements. The APIC enables administrators to select the pods, leaf switches, and interfaces to which they will apply access policies.
Access policies configure external-facing interfaces that do not connect to a spine switch. External-facing interfaces connect to external devices such as virtual machine controllers and hypervisors, hosts, routers, or fabric extenders (FEX). Access policies enable configuring port channels and virtual port channels, protocols such as LLDP, CDP or LACP, and features like monitoring or diagnostics.
Stay safe,
Sergiu